---
title: "Health-Ecore at EPH 2026: what is the potential of a combined COVID-19 and flu vaccine?"
description: Join Health-Ecore at ISPOR Europe 2025 in Glasgow to explore HEOR research on prevention, obesity, Alzheimer’s, and informal care.
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 2 min read

# Health-Ecore at EPH 2026: what is the potential of a combined COVID-19 and flu vaccine?

[![Picture of Susan de Braak](https://app.hubspot.com/settings/avatar/d41d8cd98f00b204e9800998ecf8427e) Susan de Braak](https://health-ecore.com/news/author/susan-de-braak) : Published November 9, 2026

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[The 19th European Public Health Conference](https://ephconference.eu) (EPH 2026) takes place in Bilbao, Spain, from 11 to 13 November. This year’s theme is “Urban and global synergies: shaping the future of public health with climate resilience, equity and innovation.” At the conference, we will present our analysis of the health impact of a combined COVID-19–influenza mRNA vaccine in older and high-risk Dutch adults.

Below are the session details, including date, time and presenting author.

### **Friday, 13 November 2026**

---

**14:00 | Pitch presentation |  Session K: Infectious diseases control | Room 0e\>2**

**Health impact of a combined COVID-19-influenza mRNA vaccine in older and high-risk Dutch adults** 

 

 COVID-19 vaccine uptake in the Netherlands lags well behind influenza coverage, and a combined vaccine could potentially close that gap with a single seasonal appointment. Using a decision-tree model of adults aged 60 and over and high-risk adults aged 50 and over, this study shows that replacing separate vaccines with mRNA-1083 would avert thousands of GP visits, hospitalisations and deaths each year, from both COVID-19 and influenza. It concludes that combination vaccines merit a place in Dutch strategies against seasonal respiratory disease. 

![EUPHA\_combi\_vaccine\_2560x1440](https://health-ecore.com/hs-fs/hubfs/EUPHA_combi_vaccine_2560x1440.jpg?width=2560&height=1440&name=EUPHA_combi_vaccine_2560x1440.jpg)

Curious about our research? 

[Read the full abstract](https://academic.oup.com/eurpub/article/36/Supplement_5/ckag169.630/8995130) 

Or join Session K: Infectious diseases control at EPH and meet Susan de Braak.

 

 

### **What could a combined COVID-19 and influenza vaccine mean for the Netherlands?**

---

In the Netherlands, influenza and COVID-19 vaccination are offered through two separate programmes, by different providers and at different appointments. A combination vaccine, which offers both vaccinations in a single dose, would impact the logistics around vaccination and potentially vaccination coverage. In addition, the components of the new combination vaccine mRNA-1083 may offer improved effectiveness compared with the current vaccines. Together, these could improve health outcomes and reduce the societal costs of respiratory disease and vaccination.

At the European Public Health Conference in Bilbao, results will be presented on what introducing a combination vaccine could mean for Dutch vaccination policy.

 

### **The analysis**

---

A static decision-tree model was used to simulate one respiratory year (2023/2024) among adults aged 60 and over and high-risk adults aged 50 to 59. Current policy, with a standard-dose influenza vaccine at the GP and a COVID-19 vaccine at the municipal health service, was compared with offering mRNA-1083 at the GP to everyone currently offered a flu shot. The model followed infections through several levels of care: illness without medical attention, GP visits, emergency department visits, hospital and intensive care admissions, and deaths in hospital and in nursing homes. Besides admissions directly attributable to influenza or COVID-19, it included cardiorespiratory admissions, such as heart failure and stroke, that respiratory infections can trigger. For each level of care, the number of cases averted was estimated, together with the life years and quality-adjusted life years gained. Costs averted were estimated from a societal perspective, covering healthcare use, vaccine administration and productivity losses, and excluding vaccine prices.

### **Relevance**

---

Respiratory infections put recurring pressure on GP practices, hospitals and nursing homes every season, and their impact extends beyond the infection itself, for example through cardiovascular events. Vaccination policy for influenza and COVID-19 is therefore reviewed regularly: eligibility for both programmes is reassessed, and new, enhanced vaccines are becoming available. A combination vaccine adds a further option to these considerations, one whose effectiveness and practical implementation need to be assessed. This study explores the health impact and costs of introducing a combination vaccine compared with current policy, as input for further discussion on its potential value in the Netherlands.

 

This research was conducted by Susan L. de Braak, J. Luttjeboer, T.A. Westra, V.J. Lempers, Maarten J. Postma, Cornelis Boersma and Simon van der Pol, published as a conference abstract in the European Journal of Public Health, Volume 36, Supplement 5, 2026, and funded by Moderna. Full conflict-of-interest disclosure is available in the published abstract.

References:

(1) De Braak SL, Luttjeboer J, Westra TA, Lempers VJ, Postma MJ, Boersma C, Van der Pol S. Health impact of a combined COVID-19-influenza mRNA vaccine in older and high-risk Dutch adults. Eur J Public Health. 2026;36(Suppl 5):ckag169.630. [https://doi.org/10.1093/eurpub/ckag169.630](https://doi.org/10.1093/eurpub/ckag169.630)

 

 

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